Biobank Norway 5 (BN5) is a national research infrastructure that connects biobanks, biomedical resources and health data to strengthen research, innovation and international collaboration in health and life sciences. The project will improve the visibility, accessibility and interoperability of biological samples and associated data, strengthen clinical biobanks for precision medicine, enable secure federated use of health data, and introduce a One Health perspective that integrates human, animal and environmental biobanking resources.